M Sc. Biochemistry
Note: The syllabus prescribed for the entrance test has been divided into fifteen units. Each unit carries a weightage of four marks. Paper setters are required to set four multiple choice type questions with only one correct or most appropriate answer separately for each unit, giving uniform representation to the whole syllabus contained therein.
Unit 1
Laws of thermodynamics
Concepts of heat of reaction, enthalpy, entropy
Electrochemistry
Unit 2
Electro-negativity
Acid base equilibria
Essential and trace elements in biological system
Unit 3
Concepts of chemical bonding
Electron displacements
Dipole-dipole interactions: hydrogen bond, Vander-waals forces, hydrophobic and hydrophilic interactions
Unit 4
Isomerism
Soaps and Detergents
Spectroscopy
Unit 5
Photosynthesis and its mechanism
Significance and mechanism of respiration
Importance of water to plant life.
Transpiration mechanism.
Methods of study of macro and micro nutrients availability, uptake and role
Unit 6
Ecology and environmental conservation
Air, water pollution and their control, renewable and non renewable recourses,
protection, conservation and management.
Toxicity of metals and the reasons of toxicity
Use of radioisotopes as a tracer in chemical reactions, in agriculture, industry and medicine
Concepts of Evolution, ecosystem, nitrogen, phosphorus and carbon dioxide cycle
Unit 7
Structure, transmission and role of viruses
Bacterial – morphology and their growth
Host Parasite relationship
Applications of microbiology
Unit 8
Structure, Classification, Properties and importance of Proteins, Enzymes, lipids, nucleic acids and carbohydrates
Chromosome Structure, hereditary, linkage & recombination
Unit 9
Mutation
Variation in chromosome number
DNA as genetic material, replication, transcription, Genetic Code, mechanism of protein synthesis and regulation
Various structural levels of nucleic acids
Unit 10
Restriction and modification system
Transformation, Transduction
Cell, tissue and organ culture, methods and practical applications
Unit 11
Introduction, Scope and significance of biotechnology
Elementary idea of Genetic Engineering
Unit 12
Historical Perspective, Scope and significance of developmental biology
Cell Cycle and its different stages
Morphology of cell – Prokaryotic and eukaryotic
Structure, composition and function of cell wall, plasma membrane, mitochondria, plastids, endoplasmic reticulum nucleus, nucleoli, lysosomes and ribosomes
Unit 13
Blood components and their functions
Composition and functions of lymphatic system
Overall anatomy and function of various components of human circulatory, respiratory, excretory, nervous, digestive and endocrine system
Unit 14
Glycolsis , TCA cycle, pentose phosphate pathway, Gluconeogenesis, Glycogen synthesis and breakdown,
β-oxidation of fatty acids, metabolism of fatty acid, triacylglycerol and cholesterol
Electron transport chain and oxidative phosphorylation
Transamination and deamination reactions, urea cycle, metabolism of phenylalanine, tyrosine, tryptophan.
Unit 15
Metabolism of purines and pyrimidines.
Basic concepts of immunology
Basic concepts of nutrition
Definition and scope of clinical biochemistry in diagnosis
Enzyme patterns in health and disease states with reference to plasma lipase, amylase,
cholinesterase, alkaline and acid phosphatase, SGOT, SGPT, LDH and CPK, kidney function and liver function tests.
